Product Name: ERK7 (172-179) pT175+pY177
Product Number: PE-04ATW80
Size: | 200 µg | | Price: | 16.00 |
| 1 mg | | $US | 31.00 |
Peptide Name: ERK7 (172-179) pT175+pY177
Product Use: This phosphopeptide may be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the protein kinase catalytic domain activation T-loop between subdomains VII and VIII. Phosphorylation at T175 and Y177 are predicted to be stimulatory for phosphotransferase activity.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: QAV-pT-E-pY-VA
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Peptide Modifications Other: Phosphorylated
Peptide Molecular Mass Calculated: 1213.1 Da
Peptide Purity Percent after Synthesis and Purification: <50
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Storage Stability: Not stable
Scientific Background: ERK7 (MAPK15) is a protein-serine/threonine kinase of the CMGC group and MAPK family and Erk7 subgroup. It interacts with CSK/c-Src, ABL1, RET and TGFB1I1. Phosphorylation of T175 and Y177 increases the phosphotransferase activity of ERK7.