Product Name: CDK9 (172-189) pS175+pS180+pY185+pT186
Product Number: PE-04ASR99
Size: 200 µg      Price:30.00
1 mg      $US60.00
5 mg      163.00
Peptide Name: CDK9 (172-189) pS175+pS180+pY185+pT186

Product Use: This phosphopeptide may be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the protein kinase catalytic domain activation T loop region between subdomains VII and VIII. Phosphorylation at all of these sites stimulates phosphotransferase activity.

Peptide Production Method: Solid-phase peptide synthesis

Peptide Origin: Homo sapiens

Peptide Sequence: RAF-pS-LAKN-pS-QPNR-pY-pT-NRV

Peptide Modifications N Terminus: Free amino

Peptide Modifications C Terminus: βAla-Cys

Peptide Modifications Other: Phosphorylated

Peptide Molecular Mass Calculated: 2615.5 Da

Peptide Purity Percent after Synthesis and Purification: >50

Peptide Appearance: White powder

Peptide Form: Solid

Storage Conditions: -20°C

Scientific Background: CDK9 is a protein-serine/threonine kinase of the CMGC group and CDK family. It is a protein kinase that is involved in chromatin binding and transcription regulator region DNA binding. Phosphorylation at S175 increases phosphotransferase activity.