Product Name: PCYT1B (311-321) pS315+pS319
Product Number: PE-04ARF95
| Size: | 200 µg | Price: | 18.00 | |
| $US |
Peptide Name: PCYT1B (311-321) pS315+pS319
Product Use: Services as a blocking peptide for use with the PCYT1B-pS315+pS319 rabbit polyclonal antibody (Cat. No.: AB-PN546) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located near the C-terminus of the protein. This is the main in vivo phosphorylation site in PCYT1B. The effect of its phosphorylation is unclear.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: LQAL-pS-PKQ-pS-PV
Peptide Modifications N Terminus: Free amino
Product Use: Services as a blocking peptide for use with the PCYT1B-pS315+pS319 rabbit polyclonal antibody (Cat. No.: AB-PN546) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located near the C-terminus of the protein. This is the main in vivo phosphorylation site in PCYT1B. The effect of its phosphorylation is unclear.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: LQAL-pS-PKQ-pS-PV
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Peptide Modifications Other: Phosphorylated
Peptide Molecular Mass Calculated: 1500.5 Da
Peptide Purity Percent after Synthesis and Purification: <50
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Storage Stability: Not stable
Related Product 1: PCYT1B - pS315+pS319 phosphosite-specific antibody (Cat. No.: AB-PN546)
Peptide Modifications Other: Phosphorylated
Peptide Molecular Mass Calculated: 1500.5 Da
Peptide Purity Percent after Synthesis and Purification: <50
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Storage Stability: Not stable
Related Product 1: PCYT1B - pS315+pS319 phosphosite-specific antibody (Cat. No.: AB-PN546)
Scientific Background: PCYT1B is the rate limiting enzyme in the biosynthetic pathway for phosphatidylcholine. It catalyzes the reaction: CTP + phosphocholine = diphosphate + CDP-choline. It is an ambiquitous enzyme that resides in the cytoplasm of cells in an inactive form. Diacylglycerol, acidic phospholipids and fatty acids drive the binding of PCYT1B to the endoplasmic reticulum and stimulation of its catalytic activity.
© Kinexus Bioinformatics Corporation 2017