Product Name: TIF1b (455-461) pY458
Product Number: PE-04APZ99
| Size: | 200 µg | Price: | 47.00 | |
| 1 mg | $US | 94.00 | ||
| 5 mg | 206.00 |
Peptide Name: TIF1b (455-461) pY458
Product Use: Services as a blocking peptide for use with the TRIM28-pY458 rabbit polyclonal antibody (Cat. No.: AB-PK834) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the region between the zf-B_box and PHD domains. One of the major in vivo sites of phosphorylation in TRIM28. Y458 phosphorylation stimulates interaction with HP1 alpha and induces DNA repair.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: DDP-pY-SSA
Peptide Modifications N Terminus: Free amino
Product Use: Services as a blocking peptide for use with the TRIM28-pY458 rabbit polyclonal antibody (Cat. No.: AB-PK834) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the region between the zf-B_box and PHD domains. One of the major in vivo sites of phosphorylation in TRIM28. Y458 phosphorylation stimulates interaction with HP1 alpha and induces DNA repair.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: DDP-pY-SSA
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Peptide Modifications Other: Phosphorylated
Peptide Molecular Mass Calculated: 1006.91 Da
Peptide Purity Percent after Synthesis and Purification: >95
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: TIF1b - pY458 phosphosite-specific antibody (Cat. No.: AB-PK834)
Peptide Modifications Other: Phosphorylated
Peptide Molecular Mass Calculated: 1006.91 Da
Peptide Purity Percent after Synthesis and Purification: >95
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: TIF1b - pY458 phosphosite-specific antibody (Cat. No.: AB-PK834)
Scientific Background: TRIM28 (TIF1b)) is a protein-serine/threonine kinase of the Atypical group and TIF1 family. TIF family members are associated in retroviral restriction. TRIM28 contributes to EMT via E-cadherin and N-cadherin regulation in lung cancer cell lines.
© Kinexus Bioinformatics Corporation 2017