Product Name: RIPK2 (378-384) pY381
Product Number: PE-04APJ90
Size: 200 µg      Price:41.00
1 mg      $US82.00
5 mg      194.00
Peptide Name: RIPK2 (378-384) pY381

Product Use: Services as a blocking peptide for use with the RIPK2-pY381 rabbit polyclonal antibody (Cat. No.: AB-PK797) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the region between the kinase catalytic and RHIM domains. This is a the major in vivo phosphorylation site in RIPK1. The effect of its phosphorylation is unclear.

Peptide Production Method: Solid-phase peptide synthesis

Peptide Origin: Homo sapiens

Peptide Sequence: QDA-pY-FMK

Peptide Modifications N Terminus: Free amino

Peptide Modifications C Terminus: βAla-Cys
Peptide Modifications Other: Phosphorylated

Peptide Molecular Mass Calculated: 1155.23 Da

Peptide Purity Percent after Synthesis and Purification: 90

Peptide Appearance: White powder

Peptide Form: Solid

Storage Conditions: -20°C

Related Product 1: RIPK2 - pY381 phosphosite-specific antibody (Cat. No.: AB-PK797)

Scientific Background: RIPK2 (CARD3) is a protein-serine/threonine kinase of the TKL group and RIPK family. It plays an essential role in modulation of innate and adaptive immune responses. It Is activated by phosphorylation at S176.