Product Name: RIPK2 (173-179) pS176
Product Number: PE-04API75
Peptide Name: RIPK2 (173-179) pS176
Product Use: Services as a blocking peptide for use with the RIPK2-pS176 rabbit polyclonal antibody (Cat. No.: AB-PK796) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the protein kinase catalytic domain activation T loop region between subdomains VII and VIII. S176 phosphorylation stimulates phosphotransferase activity.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: MSL-pS-QSR
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Scientific Background: RIPK2 (CARD3) is a protein-serine/threonine kinase of the TKL group and RIPK family. It plays an essential role in modulation of innate and adaptive immune responses. It Is activated by phosphorylation at S176.