Product Name: PRKX (198-206) pT201+pT203
Product Number: PE-04APD99
| Size: | 200 µg | Price: | 68.00 | |
| 1 mg | $US | 136.00 | ||
| 5 mg | 297.00 |
Peptide Name: PRKX (198-206) pT201+pT203
Product Use: Services as a blocking peptide for use with the PRKX-p T201+pT203 rabbit polyclonal antibody (Cat. No.: AB-PK785) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the protein kinase catalytic domain activation T-loop between subdomains VII and VIII. T201 and T203 phosphorylation are predicted to stimulate phosphotransferase activity.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: VDR-pT-W-pT-LCG
Peptide Modifications N Terminus: Free amino
Product Use: Services as a blocking peptide for use with the PRKX-p T201+pT203 rabbit polyclonal antibody (Cat. No.: AB-PK785) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the protein kinase catalytic domain activation T-loop between subdomains VII and VIII. T201 and T203 phosphorylation are predicted to stimulate phosphotransferase activity.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: VDR-pT-W-pT-LCG
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Peptide Modifications Other: Phosphorylated
Peptide Molecular Mass Calculated: 1383.4 Da
Peptide Purity Percent after Synthesis and Purification: >95
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: PRKX - pT201+pT203 phosphosite-specific antibody (Cat. No.: AB-PK785)
Peptide Modifications Other: Phosphorylated
Peptide Molecular Mass Calculated: 1383.4 Da
Peptide Purity Percent after Synthesis and Purification: >95
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: PRKX - pT201+pT203 phosphosite-specific antibody (Cat. No.: AB-PK785)
Scientific Background: PRKX (PKX1) is a protein-serine/threonine kinase of the AGC group and PKA family. It can control cAMP signalling, cell differentiation, epithelial morphogenesis, nephrogenesis, and angiogenesis. Downstream targets of PRKX can include SMAD6, CREB, and PKD1. SMAD6 phosphorylation mediates differentiation of myeloid cells.
© Kinexus Bioinformatics Corporation 2017