Product Name: PIP5K (304-310) pS307
Product Number: PE-04AOO99
| Size: | 200 µg | Price: | 42.00 | |
| 1 mg | $US | 84.00 | ||
| 5 mg | 185.00 |
Peptide Name: PIP5K (304-310) pS307
Product Use: Services as a blocking peptide for use with the PIP5K-pS307 rabbit polyclonal antibody (Cat. No.: AB-PK762) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the region between the FYVE and DEP domains in the N-terminal part of the kinase. S307 phosphorylation stimulates phosphotransferase activity.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: RSA-pS-ITN
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Product Use: Services as a blocking peptide for use with the PIP5K-pS307 rabbit polyclonal antibody (Cat. No.: AB-PK762) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the region between the FYVE and DEP domains in the N-terminal part of the kinase. S307 phosphorylation stimulates phosphotransferase activity.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: RSA-pS-ITN
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Peptide Modifications Other: Phosphorylated
Peptide Molecular Mass Calculated: 1001.01 Da
Peptide Purity Percent after Synthesis and Purification: >95
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: PIP5K - pS307 phosphosite-specific antibody (Cat. No.: AB-PK762)
Peptide Molecular Mass Calculated: 1001.01 Da
Peptide Purity Percent after Synthesis and Purification: >95
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: PIP5K - pS307 phosphosite-specific antibody (Cat. No.: AB-PK762)
Scientific Background: PIP5K (PIKFYVE) is a protein-serine/threonine kinase of the Atypical group. It regulates the production and degradation of phosphatidylinositol 3,5-bisphosphate. The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). It catalyzes the phosphorylation of phosphatidylinositol 3-phosphate on the fifth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 3,5-bisphosphate. It is required for endocytic-vacuolar pathway and nuclear migration, and plays a role in the biogenesis of endosome carrier vesicles (ECV)/ multivesicular bodies (MVB) transport intermediates from early endosomes.
© Kinexus Bioinformatics Corporation 2017