Product Name: PERK (889-895) pT982
Product Number: PE-04AON99
| Size: | 200 µg | Price: | 42.00 | |
| 1 mg | $US | 84.00 | ||
| 5 mg | 185.00 |
Peptide Name: PERK (889-895) pT982
Product Use: Services as a blocking peptide for use with the EIF2AK3-pT982 rabbit polyclonal antibody (Cat. No.: AB-PK604) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the protein kinase catalytic domain activation T-loop between subdomains VII and VIII. T982 phosphorylation stimulates phosphotransferase activity.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: ARH-pT-GQV
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Product Use: Services as a blocking peptide for use with the EIF2AK3-pT982 rabbit polyclonal antibody (Cat. No.: AB-PK604) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the protein kinase catalytic domain activation T-loop between subdomains VII and VIII. T982 phosphorylation stimulates phosphotransferase activity.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: ARH-pT-GQV
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Peptide Modifications Other: Phosphorylated
Peptide Molecular Mass Calculated: 1021.04 Da
Peptide Purity Percent after Synthesis and Purification: >95
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: PERK - pT982 phosphosite-specific antibody (Cat. No.: AB-PK604)
Peptide Molecular Mass Calculated: 1021.04 Da
Peptide Purity Percent after Synthesis and Purification: >95
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: PERK - pT982 phosphosite-specific antibody (Cat. No.: AB-PK604)
Scientific Background: PERK is a protein-serine/threonine kinase of the Other group and PEK family. It serves as a critical effector of unfolded protein response-induced G1 growth arrest. Perturbation in protein folding in the endoplasmic reticulum (ER) promotes reversible dissociation from HSPA5/BIP and oligomerization, resulting in transautophosphorylation and induction of its phosphotransferase activity.
© Kinexus Bioinformatics Corporation 2017