Product Name: MOS (260-266) pY263
Product Number: PE-04AOC99
| Size: | 200 µg | Price: | 47.00 | |
| 1 mg | $US | 94.00 | ||
| 5 mg | 206.00 |
Peptide Name: MOS (260-266) pY263
Product Use: Services as a blocking peptide for use with the Mos-pY263 rabbit polyclonal antibody (Cat. No.: AB-PK722) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the protein kinase catalytic domain near subdomain IX. The effect of its phosphorylation is unclear.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: ADI-pY-SFA
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Product Use: Services as a blocking peptide for use with the Mos-pY263 rabbit polyclonal antibody (Cat. No.: AB-PK722) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the protein kinase catalytic domain near subdomain IX. The effect of its phosphorylation is unclear.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: ADI-pY-SFA
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Peptide Modifications Other: Phosphorylated
Peptide Molecular Mass Calculated: 1039.05 Da
Peptide Purity Percent after Synthesis and Purification: >95
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: MOS - pY263 phosphosite-specific antibody (Cat. No.: AB-PK722)
Peptide Molecular Mass Calculated: 1039.05 Da
Peptide Purity Percent after Synthesis and Purification: >95
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: MOS - pY263 phosphosite-specific antibody (Cat. No.: AB-PK722)
Scientific Background: MOS is a protein-serine/threonine kinase of the Other group and MOS family. During oocyte maturation, it acts as a kinase that directly phosphorylates and activates MEK1 and MEK2 in the MAP kinase signalling module. It is also known as "cytostatic factor" in unfertilized oocytes. It is activated by phosphorylation at S3, and inhibited by phosphorylation at S102. Mos was originally identified as an oncoprotein from avial retroviral studies. While it phosphorylates and activates MEK1 and MEK2, there is little evidence that it functions as an oncoprotein in human cancers.
© Kinexus Bioinformatics Corporation 2017