Product Name: MEKK2 (236-242) pS239
Product Number: PE-04ANX90
| Size: | 200 µg | Price: | 37.00 | |
| 1 mg | $US | 74.00 | ||
| 5 mg | 174.00 |
Peptide Name: MEKK2 (236-242) pS239
Product Use: Services as a blocking peptide for use with the MEKK2-pS239 rabbit polyclonal antibody (Cat. No.: AB-PK700) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the region between the PB1 domain and the protein kinase catalytic domain. The effect of its phosphorylation is unclear. This is a major site of phosphorylation for MEKK2.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: RAQ-pS-YPD
Peptide Modifications N Terminus: Free amino
Product Use: Services as a blocking peptide for use with the MEKK2-pS239 rabbit polyclonal antibody (Cat. No.: AB-PK700) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the region between the PB1 domain and the protein kinase catalytic domain. The effect of its phosphorylation is unclear. This is a major site of phosphorylation for MEKK2.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: RAQ-pS-YPD
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Peptide Modifications Other: Phosphorylated
Peptide Molecular Mass Calculated: 1089.07 Da
Peptide Purity Percent after Synthesis and Purification: >90
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: MEKK2 - pS239 phosphosite-specific antibody (Cat. No.: AB-PK700)
Peptide Modifications Other: Phosphorylated
Peptide Molecular Mass Calculated: 1089.07 Da
Peptide Purity Percent after Synthesis and Purification: >90
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: MEKK2 - pS239 phosphosite-specific antibody (Cat. No.: AB-PK700)
Scientific Background: MEKK2 (MAP3K2) is a protein-serine/threonine kinase of the STE group and STE11 family. It is required for cytokine production in cultured mast cells. The protein is one of the kinases that regulate different steps of the caveolar cycle. It activated by phosphorylation on T524. Methylation of the protein increases MAP kinase signalling and promotes Ras-driven carcinomas.
© Kinexus Bioinformatics Corporation 2017