Product Name: KHS1 (28-34) pY31
Product Number: PE-04ANC90
| Size: | 200 µg | Price: | 41.00 | |
| 1 mg | $US | 82.00 | ||
| 5 mg | 194.00 |
Peptide Name: KHS1 (28-34) pY31
Product Use: Services as a blocking peptide for use with the KHS1-pY31 rabbit polyclonal antibody (Cat. No.: AB-PK672) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the protein kinase catalytic domain in subdomain I, which is involved in binding the phosphates in the ATP substrate. Y31 phosphorylation is predicted to be inhibitory for phosphotransferase activity.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: SGT-pY-GDV
Peptide Modifications N Terminus: Free amino
Product Use: Services as a blocking peptide for use with the KHS1-pY31 rabbit polyclonal antibody (Cat. No.: AB-PK672) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the protein kinase catalytic domain in subdomain I, which is involved in binding the phosphates in the ATP substrate. Y31 phosphorylation is predicted to be inhibitory for phosphotransferase activity.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: SGT-pY-GDV
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Peptide Modifications Other: Phosphorylated
Peptide Molecular Mass Calculated: 950.88 Da
Peptide Purity Percent after Synthesis and Purification: >90
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: KHS1 - pY31 phosphosite-specific antibody (Cat. No.: AB-PK672)
Peptide Modifications Other: Phosphorylated
Peptide Molecular Mass Calculated: 950.88 Da
Peptide Purity Percent after Synthesis and Purification: >90
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: KHS1 - pY31 phosphosite-specific antibody (Cat. No.: AB-PK672)
Scientific Background: KHS1 (MAP4K5) is a protein-serine/threonine kinase of the STE group and STE20 family. It has been proposed to be upstream of the JUN N-terminal pathway and may respond to environmental stresses. A mutation in KHS1, K49R, inhibits the kinase phosphotransferase activity and inhibits downstream JNK proteins.
© Kinexus Bioinformatics Corporation 2017