Product Name: GTF2F1 (382-392) pS385+pT389
Product Number: PE-04AMS95
Size: | 200 µg | | Price: | 74.00 |
| 1 mg | | $US | 148.00 |
| 5 mg | | | 325.00 |
Peptide Name: GTF2F1 (382-392) pS385+pT389
Product Use: Services as a blocking peptide for use with the GTF2F1-pS385+pT389 rabbit polyclonal antibody (Cat. No.: AB-PK651) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the TFIIF_alpha domain. Phosphorylation inhibits transcriptional activity.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: RGN-pS-RPG-pT-PSA
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Scientific Background: GTF2F1 is a protein-serine/threonine kinase of the Atypical group and family. It is also a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It can be inhibited by mutation of S385 and T389.