Product Name: DLK (266-272) pS269
Product Number: PE-04ALS85
Size: | 200 µg | | Price: | 32.00 |
| 1 mg | | $US | 63.00 |
| 5 mg | | | 137.00 |
Peptide Name: DLK (266-272) pS269
Product Use: Services as a blocking peptide for use with the DAPK -pS269 rabbit polyclonal antibody (Cat. No.: AB-PK590) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the protein kinase catalytic domain activation T loop region between subdomains VII and VIII. S269 phosphorylation is predicted to be stimulatory for phosphotransferase activity.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: TKM-pS-FAG
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Peptide Modifications Other: Phosphorylated
Peptide Molecular Mass Calculated: 995.06 Da
Peptide Purity Percent after Synthesis and Purification: >80
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: DLK - pS269 phosphosite-specific antibody (Cat. No.: AB-PK590) Scientific Background: DLK (MAP3K12) is a protein-serine/threonine kinase of the TKL group and MLK family. It is a protein kinase that has been noted as a possible JNK/SAPK pathway activator. In vivo DLK has been noted to phosphorylate beta-casein, myelin basic protein, and histone 1.