Product Name: SLK (186-192) pS189
Product Number: PE-04ALC99
Size: | 200 µg | | Price: | 42.00 |
| 1 mg | | $US | 84.00 |
| 5 mg | | | 185.00 |
Peptide Name: SLK (186-192) pS189
Product Use: Services as a blocking peptide for use with the SLK-pS189 rabbit polyclonal antibody (Cat. No.: AB-PK816) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the protein kinase catalytic domain activation T loop region between subdomains VII and VIII. S189 phosphorylation is predicted to be stimulatory for phosphotransferase activity.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: RRD-pS-FIG
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Peptide Modifications Other: Phosphorylated
Peptide Molecular Mass Calculated: 1104.13 Da
Peptide Purity Percent after Synthesis and Purification: >95
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: SLK - pS189 phosphosite-specific antibody (Cat. No.: AB-PK816) Scientific Background: SLK is a protein-serine/threonine kinase of the STE group and STE20 family. It may function in apoptosis and actin stress fiber dissolution. SLK was shown to be necessary for ErbB2-driven breast cancer cell motility.