Product Name: SLK (186-192) pS189
Product Number: PE-04ALC99
Size: 200 µg      Price:42.00
1 mg      $US84.00
5 mg      185.00
Peptide Name: SLK (186-192) pS189

Product Use: Services as a blocking peptide for use with the SLK-pS189 rabbit polyclonal antibody (Cat. No.: AB-PK816) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the protein kinase catalytic domain activation T loop region between subdomains VII and VIII. S189 phosphorylation is predicted to be stimulatory for phosphotransferase activity.

Peptide Production Method: Solid-phase peptide synthesis

Peptide Origin: Homo sapiens

Peptide Sequence: RRD-pS-FIG

Peptide Modifications N Terminus: Free amino

Peptide Modifications C Terminus: βAla-Cys

Peptide Modifications Other: Phosphorylated

Peptide Molecular Mass Calculated: 1104.13 Da

Peptide Purity Percent after Synthesis and Purification: >95

Peptide Appearance: White powder

Peptide Form: Solid

Storage Conditions: -20°C

Related Product 1: SLK - pS189 phosphosite-specific antibody (Cat. No.: AB-PK816)

Scientific Background: SLK is a protein-serine/threonine kinase of the STE group and STE20 family. It may function in apoptosis and actin stress fiber dissolution. SLK was shown to be necessary for ErbB2-driven breast cancer cell motility.