Product Name: CDK9 (344-350) pS347
Product Number: PE-04AJT99
Size: | 200 µg | | Price: | 42.00 |
| 1 mg | | $US | 84.00 |
| 5 mg | | | 185.00 |
Peptide Name: CDK9 (344-350) pS347
Product Use: Services as a blocking peptide for use with the CDK9-pS347 rabbit polyclonal antibody (Cat. No.: AB-PK574) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located near the C-terminus of the kinase after the catalytic domain. Phosphorylation induces interaction with RNA [PubMed: 10958691).
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: RKG-pS-QIT
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Scientific Background: CDK9 is a protein-serine/threonine kinase of the CMGC group and CDK family. It is a protein kinase that is involved in chromatin binding and transcription regulator region DNA binding. Phosphorylation at S175 increases phosphotransferase activity.