Product Name: CDK9 (183-189) pT186
Product Number: PE-04AJS99
| Size: | 200 µg | Price: | 42.00 | |
| 1 mg | $US | 84.00 | ||
| 5 mg | 185.00 |
Peptide Name: CDK9 (183-189) pT186
Product Use: Services as a blocking peptide for use with the CDK9-pT186 rabbit polyclonal antibody (Cat. No.: AB-PK575) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the protein kinase catalytic domain activation T loop region between subdomains VII and VIII. T186 phosphorylation stimulates phosphotransferase activity by promoting cyclin and substrate binding.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: NRY-pT-NRV
Peptide Modifications N Terminus: Free amino
Product Use: Services as a blocking peptide for use with the CDK9-pT186 rabbit polyclonal antibody (Cat. No.: AB-PK575) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the protein kinase catalytic domain activation T loop region between subdomains VII and VIII. T186 phosphorylation stimulates phosphotransferase activity by promoting cyclin and substrate binding.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: NRY-pT-NRV
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Peptide Modifications Other: Phosphorylated
Peptide Molecular Mass Calculated: 1176.18 Da
Peptide Purity Percent after Synthesis and Purification: >95
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: CDK9 - pT186 phosphosite-specific antibody (Cat. No.: AB-PK575)
Peptide Modifications Other: Phosphorylated
Peptide Molecular Mass Calculated: 1176.18 Da
Peptide Purity Percent after Synthesis and Purification: >95
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: CDK9 - pT186 phosphosite-specific antibody (Cat. No.: AB-PK575)
Scientific Background: CDK9 is a protein-serine/threonine kinase of the CMGC group and CDK family. It is a protein kinase that is involved in chromatin binding and transcription regulator region DNA binding. Phosphorylation at S175 increases phosphotransferase activity.
© Kinexus Bioinformatics Corporation 2017