Product Name: CRK7 (890-896) pT893
Product Number: PE-04AJK95
Size: | 200 µg | | Price: | 42.00 |
| 1 mg | | $US | 84.00 |
| 5 mg | | | 185.00 |
Peptide Name: CRK7 (890-896) pT893
Product Use: Services as a blocking peptide for use with the CDK12-pT893 rabbit polyclonal antibody (Cat. No.: AB-PK567) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the protein kinase catalytic domain activation T loop region between subdomains VII and VIII. T893 phosphorylation is predicted to be stimulatory for phosphotransferase activity.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: RPY-pT-NKV
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Peptide Modifications Other: Phosphorylated
Peptide Molecular Mass Calculated: 1131.18 Da
Peptide Purity Percent after Synthesis and Purification: >95
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: CRK7 - pT893 phosphosite-specific antibody (Cat. No.: AB-PK567) Scientific Background: CDK12 (CRK7) is a protein-serine/threonine kinase of the CMGC group and CDK family. Insertional mutagenesis studies in mice support a role for this protein kinase in mouse cancer oncogenesis.