Product Name: DOK3 (395-401) pY398
Product Number: PE-04AHH99
Size: | 200 µg | | Price: | 47.00 |
| 1 mg | | $US | 94.00 |
| 5 mg | | | 206.00 |
Peptide Name: DOK3 (395-401) pY398
Product Use: Services as a blocking peptide for use with the Dok3-pY398 rabbit polyclonal antibody (Cat. No.: AB-PN508) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the last quarter of the protein. This is the major in vivo phosphorylation site in Dok3. The effect of its phosphorylation is unclear.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: EHL-pY-ENL
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Scientific Background: DOK3 is an adaptor or scaffolding protein that is a negative regulator of JNK signalling in B-cells through interaction with INPP5D/SHIP1.