Product Name: SIT (92-98) pY95
Product Number: PE-04AHF95
Size: | 200 µg | | Price: | 47.00 |
| 1 mg | | $US | 94.00 |
| 5 mg | | | 206.00 |
Peptide Name: SIT (92-98) pY95
Product Use: Services as a blocking peptide for use with the SIT-pY95 rabbit polyclonal antibody (Cat. No.: AB-PN536) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the middle of the SIT domain I the protein. One of the major in vivo phosphorylation sites in SIT. The effect of its phosphorylation is unclear.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: NLH-pY-LQT
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Scientific Background: SIT negatively regulates TCR (T-cell antigen receptor)-mediated signalling in T-cells. It is involved in positive selection of T-cells.