Product Name: snRNP70 (123-129) pY126
Product Number: PE-04AFF99
Size: | 200 µg | | Price: | 47.00 |
| 1 mg | | $US | 94.00 |
| 5 mg | | | 206.00 |
Peptide Name: snRNP70 (123-129) pY126
Product Use: Services as a blocking peptide for use with the snRNP 70-pY126 rabbit polyclonal antibody (Cat. No.: AB-PN537) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the RRM_1 domain. This is the major in vivo phosphorylation site in snRNP70. The effect of its phosphorylation is unclear.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: FEV-pY-GPI
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Scientific Background: SNRNP70 is part of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and spliceosome assembly. SNRNP70 binds to the loop I region of U1-snRNA.