Product Name: ANAX1 (204-210) pY207
Product Number: PE-04AEY95
Size: | 200 µg | | Price: | 47.00 |
| 1 mg | | $US | 94.00 |
| 5 mg | | | 206.00 |
Peptide Name: ANAX1 (204-210) pY207
Product Use: Services as a blocking peptide for use with the ANXA1-pY207 rabbit polyclonal antibody (Cat. No.: AB-PN503) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the beginning of the third Annexin domain. This is the major in vivo phosphorylation site in ANXA1. The effect of its phosphorylation is unclear.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: RAL-pY-EAG
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Scientific Background: Annexin A1 plays important roles in the innate immune response as effector of glucocorticoid-mediated responses such as down-regulation of the early phase of the inflammatory response and as a regulator of the inflammatory process by promoting resolution of inflammation and wound healing. It functions at least in part by activating the formyl peptide receptors and downstream signalling.