Product Name: ErbB2IP (1101-1107) pY1104
Product Number: PE-04AER99
| Size: | 200 µg | Price: | 47.00 | |
| 1 mg | $US | 94.00 | ||
| 5 mg | 206.00 |
Peptide Name: ErbB2IP (1101-1107) pY1104
Product Use: Services as a blocking peptide for use with the ERBB2IP-pY1104 rabbit polyclonal antibody (Cat. No.: AB-PN513) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the C-terminal quarter of the protein before the PDZ domain. The major in vivo phosphorylation site in ERBB2IP. The effect of its phosphorylation is unclear.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: EGD-pY-LSY
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Product Use: Services as a blocking peptide for use with the ERBB2IP-pY1104 rabbit polyclonal antibody (Cat. No.: AB-PN513) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the C-terminal quarter of the protein before the PDZ domain. The major in vivo phosphorylation site in ERBB2IP. The effect of its phosphorylation is unclear.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: EGD-pY-LSY
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Peptide Modifications Other: Phosphorylated
Peptide Molecular Mass Calculated: 1099.04 Da
Peptide Purity Percent after Synthesis and Purification: >95
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: ErbB2IP - pY1104 phosphosite-specific antibody (Cat. No.: AB-PN513)
Peptide Molecular Mass Calculated: 1099.04 Da
Peptide Purity Percent after Synthesis and Purification: >95
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: ErbB2IP - pY1104 phosphosite-specific antibody (Cat. No.: AB-PN513)
Scientific Background: ErbB2IP acts as an adapter for the receptor ErbB2, in epithelia. By binding the unphosphorylated 'Y1248' of receptor ErbB2, it may contribute to stabilize this unphosphorylated state. It Inhibits NOD2-dependent NF-kappa-B signalling and proinflammatory cytokine secretion.
© Kinexus Bioinformatics Corporation 2017