Product Name: SIT (87-93) pY90
Product Number: PE-04AEL99
Size: | 200 µg | | Price: | 47.00 |
| 1 mg | | $US | 94.00 |
| 5 mg | | | 206.00 |
Peptide Name: SIT (87-93) pY90
Product Use: Services as a blocking peptide for use with the SIT-pY90 rabbit polyclonal antibody (Cat. No.: AB-PN535) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the Sit domain. This is the major in vivo phosphorylation site of SIT. Phosphorylation induces interaction with Grb2.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: VPL-pY-GNL
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Scientific Background: SIT negatively regulates TCR (T-cell antigen receptor)-mediated signalling in T-cells. It is involved in positive selection of T-cells.