Product Name: MAK (154-160) pT157
Product Number: PE-04ADW90
Size: | 200 µg | | Price: | 37.00 |
| 1 mg | | $US | 74.00 |
| 5 mg | | | 174.00 |
Peptide Name: MAK (154-160) pT157
Product Use: Services as a blocking peptide for use with the MAK-pT157 rabbit polyclonal antibody (Cat. No.: AB-PK689) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the protein kinase catalytic domain activation T-loop between subdomains VII and VIII. T157 phosphorylation stimulates phosphotransferase activity.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: PPY-pT-DYV
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Scientific Background: MAK is a protein-serine/threonine kinase of the CMGC group and RCK family. It has been associated with maintaining ciliary length and modulating long-term photoreceptor cell survival. MAK has been shown to phosphorylate FZR1 during different stages of cell cycle. MAK may have a role in prostate cancer chromosome stability and in spermatogenesis.