Product Name: TGM2 (366-372) pY369
Product Number: PE-04ADQ95
Size: | 200 µg | | Price: | 47.00 |
| 1 mg | | $US | 94.00 |
| 5 mg | | | 206.00 |
Peptide Name: TGM2 (366-372) pY369
Product Use: Services as a blocking peptide for use with the TGM2-pY369 rabbit polyclonal antibody (Cat. No.: AB-PN541) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the region between the Transglut_core and Transglut_C domains. This is the major in vivo phosphorylation site in TGM2. The effect of its phosphorylation is unclear.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: EGT-pY-CCG
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Scientific Background: TGM2 is a member of the transglutaminase family of enzymes that catalyzes the crosslinking of proteins and the conjugation of polyamines to proteins. The protein acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis.