Product Name: Gab1 (403-409) pY406
Product Number: PE-04ACW80
Size: | 200 µg | | Price: | 11.00 |
| 1 mg | | $US | 21.00 |
| 5 mg | | | 58.00 |
Peptide Name: Gab1 (403-409) pY406
Product Use: Services as a blocking peptide for use with the Gab1-pY406 rabbit polyclonal antibody (Cat. No.: AB-PN516) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the mid-region of the protein. This is the second major in vivo phosphorylation site of Gab1. The effect of its phosphorylation is unclear.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: QDC-pY-DIP
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Scientific Background: Gab1 is an adapter protein that plays a role in intracellular signalling cascades triggered by activated receptor-type kinases. It plays a role in FGFR1 signalling and is probably involved in signalling from the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR).