Product Name: ENO1 (41-47) pY44
Product Number: PE-04ACS99
Size: | 200 µg | | Price: | 47.00 |
| 1 mg | | $US | 94.00 |
| 5 mg | | | 206.00 |
Peptide Name: ENO1 (41-47) pY44
Product Use: Services as a blocking peptide for use with the ENO1-pY44 rabbit polyclonal antibody (Cat. No.: AB-PN511) that is also available from Kinexus. This phosphopeptide may also be useful as a substrate for screening the phosphatase activity of protein phosphatases. The peptide sequence is located in the Enolase_N domain. This is the major in vivo phosphorylation site in ENO1. The effect of its phosphorylation is unclear.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: TGI-pY-EAL
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Scientific Background: ENO1 (alpha-enolase) is a multifunctional enzyme that, as well as its role in glycolysis, plays a part in various processes such as growth control, hypoxia tolerance and allergic responses. As a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons, it also functions in the intravascular and pericellular fibrinolytic system. It may act as a tumour suppressor.