Product Name: MPP (127-149), biotinyl.
Product Number: PE-03AAS95
Size: | 200 µg | | Price: | 78.00 |
| 1 mg | | $US | 156.00 |
| 5 mg | | | 342.00 |
Peptide Name: MPP (127-149), biotinyl.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Mus musculus
Peptide Sequence: PMIHFGNDWEDRYYRENMYRYN
Peptide Modifications N Terminus: Biotin-βAla
Peptide Modifications C Terminus: Amide
Peptide Molecular Mass Calculated: 3363.9 Da
Peptide Purity Percent after Synthesis and Purification: >95
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Scientific Background: May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro). Association with GPC1 (via its heparan sulfate chains) may target PRNP to lipid rafts. It also provides Cu2+ or Zn2+ for the ascorbate-mediated GPC1 deaminase degradation of its heparan sulfate side chains.