Product Name: MPP (127-149), biotinyl.
Product Number: PE-03AAS95
Size: 200 µg      Price:78.00
1 mg      $US156.00
5 mg      342.00
Peptide Name: MPP (127-149), biotinyl.

Peptide Production Method: Solid-phase peptide synthesis

Peptide Origin: Mus musculus

Peptide Sequence: PMIHFGNDWEDRYYRENMYRYN

Peptide Modifications N Terminus: Biotin-βAla

Peptide Modifications C Terminus: Amide

Peptide Molecular Mass Calculated: 3363.9 Da

Peptide Purity Percent after Synthesis and Purification: >95

Peptide Appearance: White powder

Peptide Form: Solid

Storage Conditions: -20°C

Scientific Background: May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro). Association with GPC1 (via its heparan sulfate chains) may target PRNP to lipid rafts. It also provides Cu2+ or Zn2+ for the ascorbate-mediated GPC1 deaminase degradation of its heparan sulfate side chains.