Product Name: PKG1Subtide
Product Number: PE-01BIW95
| Size: | 200 µg | Price: | 49.00 | |
| 1 mg | $US | 97.00 | ||
| 5 mg | 213.00 |
Peptide Name: PKG1Subtide
Product Use: For assaying the phosphotransferase activity of cGMP-dependent protein kinase 1 (UniProt ID Q13976).
Peptide Production Method: Solid-phase peptide synthesis
Peptide Sequence: NRFRRRSFCEVPA
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Peptide Molecular Mass Calculated: 1811.12 Da
Peptide Purity Percent after Synthesis and Purification: 95
Peptide Appearance: White powder
Peptide Form: Solid
Product Use: For assaying the phosphotransferase activity of cGMP-dependent protein kinase 1 (UniProt ID Q13976).
Peptide Production Method: Solid-phase peptide synthesis
Peptide Sequence: NRFRRRSFCEVPA
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Peptide Molecular Mass Calculated: 1811.12 Da
Peptide Purity Percent after Synthesis and Purification: 95
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Peptide Recommended Enzyme: PKG1
Peptide Recommended Enzyme: PKG1
Scientific Background: PKG1 (PRKG1) is a protein-serine/threonine kinase of the AGC group and PKG family. It is activated by cGMP, which is generated in response to nitric oxide. Phosphorylation at T59 increases phosphotransferase activity and its affinity for cGMP Phosphorylation at T517 increases phosphotransferase activity. An R177Q mutation in AAT8 results in a constitutively active form of PKG1, which also has reduced cGMP binding.
© Kinexus Bioinformatics Corporation 2017