Peptide Name: MerSubtide
Product Use: For assaying the phosphotransferase activity of Tyrosine-protein kinase Mer; Proto-oncogene tyrosine-protein kinase MER (UniProt ID Q12866).
Peptide Production Method: Solid-phase peptide synthesis
Peptide Sequence: KKGIEDDDYYVFGG
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Peptide Molecular Mass Calculated: 1779.9 Da
Peptide Purity Percent after Synthesis and Purification: >95
Peptide Appearance: White powder
Peptide Form: Solid
Scientific Background: MERTK (Mer) is a protein-tyrosine kinase of the TK group and Axl family. It is a receptor kinase that functions in the regulation of cell survival, angiogenesis, migration and invasion, differentiation, and phagocytosis of apoptotic cells. Phosphorylation of Y749, Y753 and Y754 increases phosphotransferase activity.