Product Name: DCAMKLSubtide
Product Number: PE-01BHA90
Size: | 200 µg | | Price: | 37.00 |
| 1 mg | | $US | 74.00 |
| 5 mg | | | 174.00 |
Peptide Name: DCAMKLSubtide
Product Use: For assaying the phosphotransferase activity of Serine/threonine-protein kinase DCLK2 (UniProt ID Q8N568).
Peptide Production Method: Solid-phase peptide synthesis
Peptide Sequence: KLPRAKSELTL
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Peptide Molecular Mass Calculated: 1429.72 Da
Peptide Purity Percent after Synthesis and Purification: ~90
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Peptide Recommended Enzyme: DCAMKL
Scientific Background: DCAMKL (DCLK2) is a protein-serine/threonine kinase in the CAMK group and DCAMKL family. It has a significantly reduced C(a2+)/CAM affinity and dependence compared to other members of the CaMK family. It may play a role in the down-regulation of CRE-dependent gene activation probably by phosphorylation of the CREB coactivator CRTC2/TORC2 and the resulting retention of TORC2 in the cytoplasm.