Product Name: CAMK1Subtide
Product Number: PE-01BGM99
| Size: | 200 µg | Price: | 45.00 | |
| 1 mg | $US | 91.00 | ||
| 5 mg | 199.00 |
Peptide Name: CAMK1Subtide
Product Use: For assaying the phosphotransferase activity of calcium/calmodulin-dependent protein-serine kinase 1 alpha (UniProt ID Q14012).
Peptide Production Method: Solid-phase peptide synthesis
Peptide Sequence: GLRRRKSERNLG
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Peptide Molecular Mass Calculated: 1616.1 Da
Peptide Purity Percent after Synthesis and Purification: >95
Peptide Appearance: White powder
Peptide Form: Solid
Product Use: For assaying the phosphotransferase activity of calcium/calmodulin-dependent protein-serine kinase 1 alpha (UniProt ID Q14012).
Peptide Production Method: Solid-phase peptide synthesis
Peptide Sequence: GLRRRKSERNLG
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: βAla-Cys
Peptide Molecular Mass Calculated: 1616.1 Da
Peptide Purity Percent after Synthesis and Purification: >95
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Peptide Recommended Enzyme: CAMK1
Peptide Recommended Enzyme: CAMK1
Scientific Background: CaMK1a is a protein-serine/threonine kinase of the CAMK group and CAMK1 family. Phosphorylation at Thr-177 increases its phosphotransferase activity by approximately 25-fold in a Ca(2+)-CaM dependent manner. Thr-177 is phosphorylated by CAMKK1 or CAMKK2. CaMK1a and CaMKK1 regulate the G(O)-G(1) restriction check point for cell cycle transition in human breast cancer cells. Target substrates for CaMK1a includes CREB1, ATF1, CFTR, MYL9, and SYN1/synapsin I.
© Kinexus Bioinformatics Corporation 2017