Product Name: ZC1 (2-20)
Product Number: PE-01BFM99T
Size: | 200 µg | | Price: | 64.00 |
| 1 mg | | $US | 128.00 |
| 5 mg | | | 280.00 |
Peptide Name: ZC1 (2-20)
Product Use: Services as a blocking peptide for use with the HGK-NT rabbit polyclonal antibody (Cat. No.: AB-NK300-1) that is also available from Kinexus. The peptide sequence is located in the N-terminus.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: ANDSPAKSLVDIDLSSLRDC
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: Amide
Peptide Molecular Mass Calculated: 2118.3 Da
Peptide Purity Percent after Synthesis and Purification: >95
Scientific Background: ZC1 (HGK, MAP4K4) is a protein-serine/threonine kinase of the STE group and STE20 family. It may play a role in the response to environmental stress and cytokines such as TNF-alpha, and appears to act upstream of the JUN N-terminal pathway. ZC1 can phosphorylate SMAD1 at T322. Insertional mutagenesis studies in mice support a role for this protein kinase in mouse cancer oncogenesis.