Product Name: ZC1 (2-20)
Product Number: PE-01BFM99T
Size: 200 µg      Price:64.00
1 mg      $US128.00
5 mg      280.00
Peptide Name: ZC1 (2-20)

Product Use: Services as a blocking peptide for use with the HGK-NT rabbit polyclonal antibody (Cat. No.: AB-NK300-1) that is also available from Kinexus. The peptide sequence is located in the N-terminus.

Peptide Production Method: Solid-phase peptide synthesis

Peptide Origin: Homo sapiens

Peptide Sequence: ANDSPAKSLVDIDLSSLRDC

Peptide Modifications N Terminus: Free amino

Peptide Modifications C Terminus: Amide

Peptide Molecular Mass Calculated: 2118.3 Da

Peptide Purity Percent after Synthesis and Purification: >95

Peptide Appearance: White powder

Peptide Form: Solid

Storage Conditions: -20°C

Storage Stability: stable

Related Product 1: ZC1 pan-specific antibody (Cat. No.: AB-NK300-1)

Scientific Background: ZC1 (HGK, MAP4K4) is a protein-serine/threonine kinase of the STE group and STE20 family. It may play a role in the response to environmental stress and cytokines such as TNF-alpha, and appears to act upstream of the JUN N-terminal pathway. ZC1 can phosphorylate SMAD1 at T322. Insertional mutagenesis studies in mice support a role for this protein kinase in mouse cancer oncogenesis.