Product Name: PKN2 (637-655)
Product Number: PE-01BEY99
| Size: | 1 mg | Price: | 128.00 | |
| 5 mg | $US | 280.00 | ||
| 20 mg | 512.00 |
Peptide Name: PKN2 (637-655)
Product Use: Services as a blocking peptide for use with the PKN2-BKCD rabbit polyclonal antibody (Cat. No.: AB-NK149-3) that is also available from Kinexus. The peptide sequence is located just before the kinase catalytic domain.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: CGIQELEDRRSQQRFQFNLQ
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: Amide
Peptide Molecular Mass Calculated: 2494.7 Da
Peptide Purity Percent after Synthesis and Purification: >95
Product Use: Services as a blocking peptide for use with the PKN2-BKCD rabbit polyclonal antibody (Cat. No.: AB-NK149-3) that is also available from Kinexus. The peptide sequence is located just before the kinase catalytic domain.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: CGIQELEDRRSQQRFQFNLQ
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: Amide
Peptide Molecular Mass Calculated: 2494.7 Da
Peptide Purity Percent after Synthesis and Purification: >95
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: PKN2 pan-specific antibody (Cat. No.: AB-NK149-3)
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: PKN2 pan-specific antibody (Cat. No.: AB-NK149-3)
Scientific Background: PKN2 is a protein-serine/threonine kinase of the AGC group and PKN family. It is a PKC-related protein-kinase that is also a Rho/Rac effector protein. It has been linked to the regulation of a wide range of cellular processes, including transcription, cell cycle progression, actin cytoskeleton assembly, cell migration and adhesion, and tumour cell invasion. PKN2 is activated by lipids, particularly cardiolipin and to a lesser extent by other acidic phospholipids and unsaturated fatty acids. Phosphorylation at T816 (activation loop of the kinase domain) and T958 (turn motif) increases phosphotransferase activity.
© Kinexus Bioinformatics Corporation 2017