Product Name: PKG1 (326-344)
Product Number: PE-01BEV99
| Size: | 200 µg | Price: | 64.00 | |
| 1 mg | $US | 128.00 | ||
| 5 mg | 280.00 |
Peptide Name: PKG1 (326-344)
Product Use: Services as a blocking peptide for use with the PKG1-BKCD rabbit polyclonal antibody (Cat. No.: AB-NK202-2) that is also available from Kinexus. The peptide sequence is located just before the kinase catalytic domain.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: CGGLDDVSNKAYEDAEAKAK
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: Amide
Peptide Molecular Mass Calculated: 2083.2 Da
Peptide Purity Percent after Synthesis and Purification: >95
Product Use: Services as a blocking peptide for use with the PKG1-BKCD rabbit polyclonal antibody (Cat. No.: AB-NK202-2) that is also available from Kinexus. The peptide sequence is located just before the kinase catalytic domain.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: CGGLDDVSNKAYEDAEAKAK
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: Amide
Peptide Molecular Mass Calculated: 2083.2 Da
Peptide Purity Percent after Synthesis and Purification: >95
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: PKG1 pan-specific antibody (Cat. No.: AB-NK202-2)
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: PKG1 pan-specific antibody (Cat. No.: AB-NK202-2)
Scientific Background: PKG1 (PRKG1) is a protein-serine/threonine kinase of the AGC group and PKG family. It is activated by cGMP, which is generated in response to nitric oxide. Phosphorylation at T59 increases phosphotransferase activity and its affinity for cGMP Phosphorylation at T517 increases phosphotransferase activity. An R177Q mutation in AAT8 results in a constitutively active form of PKG1, which also has reduced cGMP binding.
© Kinexus Bioinformatics Corporation 2017