Product Name: PIM3 (23-41)
Product Number: PE-01BET85
| Size: | 200 µg | Price: | 48.00 | |
| 1 mg | $US | 96.00 | ||
| 5 mg | 208.00 |
Peptide Name: PIM3 (23-41)
Product Use: Services as a blocking peptide for use with the Pim3-ANT rabbit polyclonal antibody (Cat. No.: AB-NK289-1) that is also available from Kinexus. The peptide sequence is located in the post-N-terminus.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: CVKILQPAKADKESFEKAYQ
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: Amide
Peptide Molecular Mass Calculated: 2295.6 Da
Peptide Purity Percent after Synthesis and Purification: >80
Product Use: Services as a blocking peptide for use with the Pim3-ANT rabbit polyclonal antibody (Cat. No.: AB-NK289-1) that is also available from Kinexus. The peptide sequence is located in the post-N-terminus.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: CVKILQPAKADKESFEKAYQ
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: Amide
Peptide Molecular Mass Calculated: 2295.6 Da
Peptide Purity Percent after Synthesis and Purification: >80
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: PIM3 pan-specific antibody (Cat. No.: AB-NK289-1)
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: PIM3 pan-specific antibody (Cat. No.: AB-NK289-1)
Scientific Background: Pim3 is a protein-serine/threonine kinase of the CAMK group and PIM family. The Pim3 protein, along with the related Pim1 and Pim2 proteins, facilitates cell survival and proliferation by acting downstream of cytokine and growth factor signalling pathways. It can prevent apoptosis, and promote cell survival and protein translation. It appears to be a tumour requiring protein (TRP), since it undergoes fewer mutations than the typical protein in cancer cells. The active form of the protein kinase normally acts to promote tumour cell proliferation. Pim3 promotes tumourigenesis, and is upregulated in human pancreatic cancer tissue and pancreatic cancer cell lines.
© Kinexus Bioinformatics Corporation 2017