Product Name: DMPK1 (407-425)
Product Number: PE-01BCR70
| Size: | 200 µg | Price: | 14.00 | |
| 1 mg | $US | 27.00 | ||
| 5 mg | 74.00 |
Peptide Name: DMPK1 (407-425)
Product Use: Services as a blocking peptide for use with the DMPK1-AKCD rabbit polyclonal antibody (Cat. No.: AB-NK264-1) that is also available from Kinexus. The peptide sequence is located just after kinase catalytic domain.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: CMALRDSEVPGPTPMELEA
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: Amide
Peptide Molecular Mass Calculated: 2045.3 Da
Peptide Purity Percent after Synthesis and Purification: >50
Product Use: Services as a blocking peptide for use with the DMPK1-AKCD rabbit polyclonal antibody (Cat. No.: AB-NK264-1) that is also available from Kinexus. The peptide sequence is located just after kinase catalytic domain.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: CMALRDSEVPGPTPMELEA
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: Amide
Peptide Molecular Mass Calculated: 2045.3 Da
Peptide Purity Percent after Synthesis and Purification: >50
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: DMPK1 pan-specific antibody (Cat. No.: AB-NK264-1)
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: DMPK1 pan-specific antibody (Cat. No.: AB-NK264-1)
Scientific Background: DMPK1 is a protein-serine/threonine kinase of the AGC group and DMPK family. It is a protein kinase that is essential for maintaining skeletal muscle structure and function. It is activated in response to G protein second messengers. Proteolytic processing of the C-terminus may remove the transmembrane domain and release the kinase from membranes stimulating its activity. Phosphorylation by Raf1 may result in activation of DMPK. It is maintained in an inactive conformation by the negative autoregulatory C-terminal coiled-coil region.
© Kinexus Bioinformatics Corporation 2017