Product Name: CDK10 (15-32)
Product Number: PE-01BCL85
Size: | 200 µg | | Price: | 43.00 |
| 1 mg | | $US | 86.00 |
| 5 mg | | | 187.00 |
Peptide Name: CDK10 (15-32)
Product Use: Services as a blocking peptide for use with the CDK10-ANT rabbit polyclonal antibody (Cat. No.: AB-NK033-2) that is also available from Kinexus. The peptide sequence is located in the post-N-terminus.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: CIRKEGFFTVPPEHRLGR
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: Amide
Peptide Molecular Mass Calculated: 2141.5 Da
Peptide Purity Percent after Synthesis and Purification: >80
Scientific Background: CDK10 (PISSLRE) is a protein-serine/threonine kinase of the CMGC group and CDK family. It is a protein kinase that mediates phosphorylation and degradation of ETS2 (a transcription factor). CDK10 appears to be a tumour requiring protein (TRP). It displays one of the lowest rates of mutation in human tumours. The near absence of reported somatic mutations in this protein indicates that it may function as a tumour requiring protein (TRP) in many human tumours.