Product Name: SHIP2 (1244-1258)
Product Number: PE-01BBU90
| Size: | 200 µg | Price: | 45.00 | |
| 1 mg | $US | 90.00 | ||
| 5 mg | 211.00 |
Peptide Name: SHIP2 (1244-1258)
Product Use: Services as a blocking peptide for use with the SHIP2-3 rabbit polyclonal antibody (Cat. No.: AB-NP045-3) that is also available from Kinexus. The peptide sequence is located in the C-terminus.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: CPAHKRLLLDTLQLSK
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: Amide
Peptide Molecular Mass Calculated: 1836.2 Da
Peptide Purity Percent after Synthesis and Purification: >90
Product Use: Services as a blocking peptide for use with the SHIP2-3 rabbit polyclonal antibody (Cat. No.: AB-NP045-3) that is also available from Kinexus. The peptide sequence is located in the C-terminus.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: CPAHKRLLLDTLQLSK
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: Amide
Peptide Molecular Mass Calculated: 1836.2 Da
Peptide Purity Percent after Synthesis and Purification: >90
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: SHIP2 pan-specific antibody (Cat. No.: AB-NP045-3)
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: SHIP2 pan-specific antibody (Cat. No.: AB-NP045-3)
Scientific Background: SHIP2 (INPPL1) is a phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3) to produce PtdIns(3,4)P2, and negatively regulate the PI3K (phosphoinositide 3-kinase) pathways. While overexpression reduces both insulin-stimulated MAP kinase and Akt activation, its absence does not affect insulin signalling or GLUT4 trafficking. It confers resistance to dietary obesity. It may also hydrolyze PtdIns(1,3,4,5)P4.
© Kinexus Bioinformatics Corporation 2017