Product Name: PDHK3 (1-15)
Product Number: PE-01BAC95
| Size: | 1 mg | Price: | 102.00 | |
| 5 mg | $US | 224.00 | ||
| 20 mg | 410.00 |
Peptide Name: PDHK3 (1-15)
Product Use: Services as a blocking peptide for use with the PDK3-1 rabbit polyclonal antibody (Cat. No.: AB-NN181-1) that is also available from Kinexus. The peptide sequence is located in the N-terminus.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: MRLFRWLLKQPVPKQC
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: Amide
Peptide Molecular Mass Calculated: 2042.6 Da
Peptide Purity Percent after Synthesis and Purification: >95
Product Use: Services as a blocking peptide for use with the PDK3-1 rabbit polyclonal antibody (Cat. No.: AB-NN181-1) that is also available from Kinexus. The peptide sequence is located in the N-terminus.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: MRLFRWLLKQPVPKQC
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: Amide
Peptide Molecular Mass Calculated: 2042.6 Da
Peptide Purity Percent after Synthesis and Purification: >95
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: PDHK3 pan-specific antibody (Cat. No.: AB-NN181-1)
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: PDHK3 pan-specific antibody (Cat. No.: AB-NN181-1)
Scientific Background: PDHK3 (PDK3) is a protein-serine/threonine kinase of the Atypical group and PDHK family. It phosphorylates and inactivates the enzyme pyruvate dehydrogenase. It is mostly expressed in the heart and skeletal muscles, and it regulates glucose metabolism and maintenance of glucose homeostasis under starvation. Inactivation of PDHK3 signalling drives melanomas towards oxidative metabolism and allows for the possibility of using pro-oxidants as therapies. PDHK3 has been shown to be overexpressed in colon cancer cell lines.
© Kinexus Bioinformatics Corporation 2017