Product Name: WNK3 (1-15)
Product Number: PE-01AZE99
| Size: | 200 µg | Price: | 51.00 | |
| 1 mg | $US | 102.00 |
Peptide Name: WNK3 (1-15)
Product Use: Services as a blocking peptide for use with the WNK3-1 rabbit polyclonal antibody (Cat. No.: AB-NK254-1) that is also available from Kinexus. The peptide sequence is located in the N-terminus.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: MATDSGDPASTEDSEC
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: Amide
Peptide Molecular Mass Calculated: 1614.6 Da
Peptide Purity Percent after Synthesis and Purification: >95
Product Use: Services as a blocking peptide for use with the WNK3-1 rabbit polyclonal antibody (Cat. No.: AB-NK254-1) that is also available from Kinexus. The peptide sequence is located in the N-terminus.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: MATDSGDPASTEDSEC
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: Amide
Peptide Molecular Mass Calculated: 1614.6 Da
Peptide Purity Percent after Synthesis and Purification: >95
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: WNK3 pan-specific antibody (Cat. No.: AB-NK254-1)
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: WNK3 pan-specific antibody (Cat. No.: AB-NK254-1)
Scientific Background: Wnk3 (PRKWNK2) is a protein-serine/threonine kinase of the Other group and Wnk family. Activation requires autophosphorylation of S308. Phosphorylation of S304 also promotes increased activity. Interestingly, Wnk3 lacks the catalytic lysine in subdomain II that is believed to be critical for phoshotransferase activity, and instead has a conserved lysine in subdomain I. It functions as a positive regulator of the transcellular Ca2+ transport pathway, and it plays a role in the increase of cell survival in a caspase-3-dependent pathway.
© Kinexus Bioinformatics Corporation 2017