Product Name: MEKK2 (602-616)
Product Number: PE-01AXV99
Size: | 200 µg | | Price: | 51.00 |
| 1 mg | | $US | 102.00 |
| 5 mg | | | 224.00 |
Peptide Name: MEKK2 (602-616)
Product Use: Services as a blocking peptide for use with the MEKK2-3 rabbit polyclonal antibody (Cat. No.: AB-NK108-5) that is also available from Kinexus. The peptide sequence is located in the kinase catalytic domain last alpha-chain.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: CKLRPSADELLRHMFV
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: Amide
Peptide Molecular Mass Calculated: 1914.31 Da
Peptide Purity Percent after Synthesis and Purification: >95
Scientific Background: MEKK2 (MAP3K2) is a protein-serine/threonine kinase of the STE group and STE11 family. It is required for cytokine production in cultured mast cells. The protein is one of the kinases that regulate different steps of the caveolar cycle. It activated by phosphorylation on T524. Methylation of the protein increases MAP kinase signalling and promotes Ras-driven carcinomas.