Product Name: MEK5 (435-448)
Product Number: PE-01AWA99
Size: 200 µg      Price:45.00
1 mg      $US90.00
5 mg      196.00
Peptide Name: MEK5 (435-448)

Product Use: Services as a blocking peptide for use with the MEK5-3 rabbit polyclonal antibody (Cat. No.: AB-NK104-5) that is also available from Kinexus. The peptide sequence is located in the C-terminus.

Peptide Production Method: Solid-phase peptide synthesis

Peptide Origin: Homo sapiens

Peptide Sequence: CRALEERRSQQGPP

Peptide Modifications N Terminus: Free amino

Peptide Modifications C Terminus: Free carboxyl

Peptide Molecular Mass Calculated: 1625.82 Da

Peptide Purity Percent after Synthesis and Purification: >95
Peptide Appearance: White powder

Peptide Form: Solid

Storage Conditions: -20°C

Related Product 1: MEK5 pan-specific antibody (Cat. No.: AB-NK104-5)

Scientific Background: MEK5 (MAP2K5) is a Dual specificity protein kinase of the STE group and STE7 family. It is activated by phosphorylation on Ser/Thr by MAP kinase kinase kinases. Activation of this pathway appear to play a critical role in protecting cells from stress-induced apopotosis, neuronal survival and cardiac development and angiogenesis by acting as a scaffold protein for the construction of a complex consisting of MAP3K2 or MAP3K3 and MAP3K5 and MAPK7.