Product Name: MEK5 (411-425)
Product Number: PE-01AVZ99
Size: | 200 µg | | Price: | 51.00 |
| 1 mg | | $US | 102.00 |
| 5 mg | | | 224.00 |
Peptide Name: MEK5 (411-425)
Product Use: Services as a blocking peptide for use with the MEK5-2 rabbit polyclonal antibody (Cat. No.: AB-NK104-4) that is also available from Kinexus. The peptide sequence is located in the kinase catalytic domain last alpha-chain.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: CEELMGHPFIVQFNDG
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: Amide
Peptide Molecular Mass Calculated: 1836 Da
Peptide Purity Percent after Synthesis and Purification: >95
Scientific Background: MEK5 (MAP2K5) is a Dual specificity protein kinase of the STE group and STE7 family. It is activated by phosphorylation on Ser/Thr by MAP kinase kinase kinases. Activation of this pathway appear to play a critical role in protecting cells from stress-induced apopotosis, neuronal survival and cardiac development and angiogenesis by acting as a scaffold protein for the construction of a complex consisting of MAP3K2 or MAP3K3 and MAP3K5 and MAPK7.