Product Name: MEK5 (411-425)
Product Number: PE-01AVZ99
Size: 200 µg      Price:51.00
1 mg      $US102.00
5 mg      224.00
Peptide Name: MEK5 (411-425)

Product Use: Services as a blocking peptide for use with the MEK5-2 rabbit polyclonal antibody (Cat. No.: AB-NK104-4) that is also available from Kinexus. The peptide sequence is located in the kinase catalytic domain last alpha-chain.

Peptide Production Method: Solid-phase peptide synthesis

Peptide Origin: Homo sapiens

Peptide Sequence: CEELMGHPFIVQFNDG

Peptide Modifications N Terminus: Free amino

Peptide Modifications C Terminus: Amide

Peptide Molecular Mass Calculated: 1836 Da

Peptide Purity Percent after Synthesis and Purification: >95

Peptide Appearance: White powder

Peptide Form: Solid

Storage Conditions: -20°C

Related Product 1: MEK5 pan-specific antibody (Cat. No.: AB-NK104-4)

Scientific Background: MEK5 (MAP2K5) is a Dual specificity protein kinase of the STE group and STE7 family. It is activated by phosphorylation on Ser/Thr by MAP kinase kinase kinases. Activation of this pathway appear to play a critical role in protecting cells from stress-induced apopotosis, neuronal survival and cardiac development and angiogenesis by acting as a scaffold protein for the construction of a complex consisting of MAP3K2 or MAP3K3 and MAP3K5 and MAPK7.