Product Name: MEK2 (360-374)
Product Number: PE-01AVW90
Size: | 200 µg | | Price: | 45.00 |
| 1 mg | | $US | 90.00 |
Peptide Name: MEK2 (360-374)
Product Use: Services as a blocking peptide for use with the MEK2 rabbit polyclonal antibody (Cat. No.: AB-NK100-4P) that is also available from Kinexus. The peptide sequence is located in the kinase catalytic domain last alpha-chain.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: CLKMLTNHTFIKRSEV
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: Amide
Peptide Molecular Mass Calculated: 1919.3 Da
Peptide Purity Percent after Synthesis and Purification: >90
Scientific Background: MEK2 (MAP2K2) is a Dual specificity protein kinase of the STE group and STE7 family. Phosphorylation of S222 and S226 increases its phosphotransferase activity. Phosphorylation of S216 inhibits phosphotransferase activity. It controls the concomitant phosphorylation of the threonine and tyrosine in a Thr-Glu-Tyr sequence in MAP kinases. It particularly targets and activates the ERK1 and ERK2 MAP kinases.