Product Name: SMG1 (67-81)
Product Number: PE-01ATH90
| Size: | 200 µg | Price: | 38.00 | |
| 1 mg | $US | 77.00 | ||
| 5 mg | 166.00 |
Peptide Name: SMG1 (67-81)
Product Use: Services as a blocking peptide for use with the SMG1 rabbit polyclonal antibody (Cat. No.: AB-NK233) that is also available from Kinexus.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: CSRQRHDDTRVHADIQ
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: Amide
Peptide Molecular Mass Calculated: 1936 Da
Peptide Purity Percent after Synthesis and Purification: >80
Peptide Appearance: White powder
Product Use: Services as a blocking peptide for use with the SMG1 rabbit polyclonal antibody (Cat. No.: AB-NK233) that is also available from Kinexus.
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: CSRQRHDDTRVHADIQ
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: Amide
Peptide Molecular Mass Calculated: 1936 Da
Peptide Purity Percent after Synthesis and Purification: >80
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Related Product 1: SMG1 pan-specific antibody (Cat. No.: AB-NK233)
Storage Conditions: -20°C
Related Product 1: SMG1 pan-specific antibody (Cat. No.: AB-NK233)
Scientific Background: SMG1 (ATX) is a protein-serine/threonine kinase of the Atypical group and PIKK family. It mediates the genotoxic stress pathway as well as the mRNA surveillance pathway. SMG1 will target nonsense RNA molecules for degradation via phosphorylation of RENT1/UPF1. SMG1 is essential for optimal phosphorylation and activity of p53/TP53 following genotoxic stress. It is iInhibited by caffeine, LY294002 and wortmannin.
© Kinexus Bioinformatics Corporation 2017