Product Name: Syntide-2 KinSub
Product Number: PE-01AQB95
Size: 200 µg      Price:48.00
1 mg      $US96.00
5 mg      210.00
Peptide Name: Syntide-2 KinSub

Product Use: For assaying the phosphotransferase activity of calcium/calmodulin-dependent protein-serine kinase 2 alpha (CaMK2a, UniProt ID Q9UQM7) and protein kinase C isoforms.

Peptide Production Method: Solid-phase peptide synthesis

Peptide Sequence: PLARTLSVAGLPGKK

Peptide Modifications N Terminus: Free amino

Peptide Modifications C Terminus: Amide

Peptide Molecular Mass Calculated: 1506.8 Da

Peptide Purity Percent after Synthesis and Purification: >95

Peptide Appearance: White powder

Peptide Form: Solid
Storage Conditions: -20°C

Peptide Recommended Enzyme: CaMK2a; PKC isoforms.

Scientific Background: CaMK2a is a protein-serine/threonine kinase of the CAMK group and CAMK2 family. It is a calcium/calmodulin-activated protein kinase involved in neurotransmitter release and long term potentiation in neurons. Autophosphorylation of Thr-286 allows the kinase to switch from a calmodulin-dependent to a calmodulin-independent state
References

[1] Kumar KA. and Babu PP. Neurosci. Lett. 336, 121 (2003);

[2] Inoue S. et al. Biochem. Biophys. Res. Commun. 215, 861 (1995);

[3] Hashimoto, Y. and TR. Soderling, Arch. Biochem. Biophys. 252, 418 (1987).