Product Name: YPFCEC
Product Number: PE-01AQA90
| Size: | 200 µg | Price: | 22.00 | |
| 1 mg | $US | 45.00 |
Peptide Name: YPFCEC
Peptide Production Method: Solid-phase peptide synthesis
Peptide Sequence: YPFCEC
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: Amide
Peptide Molecular Mass Calculated: 759.82 Da
Peptide Purity Percent after Synthesis and Purification: >90
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Peptide Production Method: Solid-phase peptide synthesis
Peptide Sequence: YPFCEC
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: Amide
Peptide Molecular Mass Calculated: 759.82 Da
Peptide Purity Percent after Synthesis and Purification: >90
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Scientific Background: MLTK (ZAK) is a protein-serine/threonine kinase of the TKL group and MLK family. It is activated by phosphorylation by PKN1 and autophosphorylation on T161 and S165. It has a pro-apoptotic activity and mediates cell cycle arrest and checkpoint regulation. It regulates the JNK and p38 pathways. Involved in regulation of S and G2 cell cycle checkpoints by direct phosphorylation of Chk2. MLTK causes cell shrinkage and disruption of actin stress fibers and phosphorylates histone H3 at S28. It has been suggested to play a role in cell transformation and oncogenesis.
© Kinexus Bioinformatics Corporation 2017