Product Name: Histone H2A (22-30)
Product Number: PE-01APX95
Size: | 200 µg | | Price: | 29.00 |
| 1 mg | | $US | 58.00 |
Peptide Name: Histone H2A (22-30)
Peptide Production Method: Solid-phase peptide synthesis
Peptide Origin: Homo sapiens
Peptide Sequence: AGLQFPVGR
Peptide Modifications N Terminus: Free amino
Peptide Modifications C Terminus: Amide
Peptide Molecular Mass Calculated: 944.2 Da
Peptide Purity Percent after Synthesis and Purification: >95
Peptide Appearance: White powder
Peptide Form: Solid
Storage Conditions: -20°C
Scientific Background: HH2A is a core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.
References[1] Williams, K.E., Carver, T.A., Miranda, JJ.L., Kautiainen, A., Vogel J.S., Dingley, K., Baldwin, M.A., Turteltaub, K.W., Burlingame A.L. (2002) Attomole Detection of in Vivo Protein Targets of Benzene in Mice. Mol. Cell. Proteomics, 1, 885-895.